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大鼠CD86 Elisa試劑盒
物品單位 價格 品牌
2600 Solarbio
  • 產地:北京
  • 貨號:SEKR-0083
  • 發布日期: 2020-08-10
  • 更新日期: 2020-08-10
產品詳細說明
產地 北京
保存條件 -20
品牌 Solarbio
貨號 SEKR-0083
檢測方法 雙抗體夾心法
CAS編號
保質期
規格
適應物種 Rat
檢測限 4.7-300 pg/mL
數量 999
用途范圍 Rat
標記物
純度 %
樣本 血清/血漿/細胞培養上清
應用 Elisa試劑盒
是否進口
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.
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