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Anti-GAPDH Polyclonal Antibody K106389P
物品單位 價格 品牌
780 solarbio
  • 產地:北京
  • 貨號:K106389P
  • 發布日期: 2020-03-20
  • 更新日期: 2020-03-20
產品詳細說明
產地 北京
品牌 solarbio
貨號 K106389P
用途 Polyclonal Antibody
產品規格 100ul
CAS編號
純度 PBS with 0.03% Proclin300, 50% glycerol, pH7.3.%
是否進口
英文名稱Anti-GAPDH Polyclonal Antibody
宿主Rabbit
別名GAPD;CDABP0047;OK/SW-cl.12;G3PD;HEL-S-162eP
應用WB
稀釋比例WB 1:5000.
交叉反應Human Mouse Rat
蛋白分子量36kDa
Gene ID2597
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human GAPDH
性狀液體
Public Immunogen RangeRecombinant protein of human GAPDH
Swiss ProtP04406
Subcellular LocationsCytoplasm Membrane Nucleus cytoskeleton cytosol perinuclear region
*類型Polyclonal Antibody
背景資料Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits.


參考文獻:


《Neuronostatin promotes soluble Aβ1-42 oligomers –induced spatial learning and memory impairments in mice》 作者:Shaobin Yang,Tingji Shao,Peng Yua,Ruidong Cao,Mingyu Zhang Kang Wen,Maorong Fan Bosheng He 期刊:Behavioural Brain Research 影響因子:2.77 PMID:30753874



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