產品目錄
Anti-DYRK1A Polyclonal Antibody / 50μl
物品單位 價格 品牌
960 solarbio
  • 產地:北京
  • 貨號:K001710P
  • 發布日期: 2018-07-13
  • 更新日期: 2018-07-31
產品詳細說明
產地 北京
品牌 solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
貨號 K001710P
應用范圍 WB
CAS編號
抗體名 Anti-DYRK1A Polyclonal Antibody
克隆性
靶點 1支/50μl/960RMB
適應物種 Human Mouse Rat
形態 Lyophilized or Liquid
宿主 Rabbit
亞型 IgG
標識物
濃度 %
免疫原 Recombinant protein of human DYRK1A
英文名稱Rabbit DYRK1A Polyclonal Antibody
別名DYRK;DYRK1;HP86;MNB;MNBH;MRD7 
應用WB
稀釋比例WB1:500-1:1000
交叉反應Human Mouse Rat
蛋白分子量86kDa
Gene ID1859
保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
儲存液PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原Recombinant protein of human DYRK1A
性狀Lyophilized or Liquid
Swiss ProtQ13627
克隆類型Polyclonal Antibody
來源Rabbit
背景資料This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.


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